neutralizing anti-il-10 (23738) (R&D Systems)

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R&D Systems neutralizing anti-il-10 (23738)
Neutralizing Anti Il 10 (23738), supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neutralizing+anti-il-10+(23738)/m+csf/pm16888088-30-1-14
Average 90 stars, based on 1 article reviews

neutralizing anti-il-10 (23738) - by Bioz Stars, 2026-09

90/100 stars

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Cell Culture:

Article Title: Filarial Infection Suppresses Malaria-Specific Multifunctional Th1 and Th17 Responses in Malaria and Filarial Coinfections
Article Snippet: .. Separate blood samples stimulated with PfSL were also cultured in the presence of 20 μg/ml neutralizing anti-human IL-10 or an isotype-matched control Ab (R&D Systems, Minneapolis, MN). .. Brefeldin A (20 μg/ml final concentration; Sigma-Aldrich, St. Louis, MO) was added to the samples after 12 h of incubation.

Article Title: Cutaneous diffuse large B-cell lymphoma induces a macrophage immunosuppressive phenotype through IL-10 secretion
Article Snippet: .. For these experiments, neutralizing anti-human IL-10 (clone number 23738) or anti-human IL-10RA (clone number 37607; R&D Systems) suitable for cell culture was used. ..

Article Title: Cutaneous diffuse large B-cell lymphoma induces a macrophage immunosuppressive phenotype through IL-10 secretion.
Article Snippet: .. 142 Anti IL-10 and anti-IL-10RA treatment 143 For these experiments, neutralizing anti-human-IL-10 (clone#23738) or anti-human-IL-144 10RA (clone#37607) (R&D Systems) suitable for cell culture were used. ..

Control:

Article Title: Different immunosuppressive mechanisms in multi-drug-resistant tuberculosis and non-tuberculous mycobacteria patients
Article Snippet: Cells were cultured subsequently in 96- or 24-well plates (Costar Corporation, Cambridge, MA, USA) at 37°C, 5% CO 2 and stimulated with 5 or 10 μg/ml ESAT-6 or phytohaemagglutinin 1% (PHA; Sigma Chemical Co., St Louis, MO, USA) for 72 h (for flow cytometry analysis) or 5 days (for measurement of protein release). .. In parallel experiments, rESAT-6 was used to stimulate cells in culture in the presence of human anti-IL-10 or human anti-IL-10Rα neutralizing antibodies (R&D Systems Inc., Minneapolis, MN, USA) at 10 μg/ml or the respective isotype control. .. CD4 + T cells were isolated from PBMC by negative selection (Miltenyi Biotec, Bergisch Gladbach, Germany), then CD4 + CD25 + T cells were selected positively from CD4 + T cells using a human CD4 + CD25 + T reg isolation kit, according to the manufacturer's instructions (Miltenyi Biotec).

other:

Article Title: HSP60, HSP60 peptides and T cell vaccines for immunomodulation
Article Snippet: Neutralizing antibodies anti-IL-10 (clone 23738.11) and anti-TGF-β (clone 9016) were purchased from R&D Systems (Minneapolis, Minn.).

Blocking Assay:

Article Title: TNF-α blockade induces IL-10 expression in human CD4+ T cells
Article Snippet: Transwell experiments were performed using a 0.4 μm semi-permeable membrane insert (Corning). .. Where indicated, FcγR blocking reagent (10 μl/ml, Miltenyi Biotec), blocking TNFRI/II Ab (5 μg/ml, R&D Systems), neutralizing anti-IL-10 mAb (clone 23738, 10 μg/ml, R&D Systems), blocking IL-10R mAb (clone 37607, 10μg/ml, R&D Systems), hrTNF-α (10ng/ml, R&D Systems) or hrIL-1β (10 ng/ml, R&D Systems) were added at the start of the co-culture. ..

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